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M94A0698.TXT
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1994-10-21
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Document 0698
DOCN M94A0698
TI Mediastinal tuberculosis with oesophageal perforation.
DT 9412
AU Dore G; St Vincent's Hospital, Darlinghurst, Sydney.
SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:32 (abstract no. FC2).
Unique Identifier : AIDSLINE ASHM5/94348957
AB A 43 year old homosexual man, known seropositive for Human
Immunodeficiency Virus (HIV) since 1984, with a CD4 Lymphocyte count of
40 x 109/ml, but with no prior Acquired Immunodeficiency Syndrome (AIDS)
defining illness, presented with a three-week history of fevers,
non-productive cough, pleuritic chest pain and dysphagia. Physical
examination revealed normal chest auscultation, no lymphadenopathy or
hepatosplenomegaly. A chest x-ray showed some widening of the superior
mediastinum, but the lung fields were clear. Endoscopic examination
revealed a perforated oesophageal ulcer at 30 centimetres, and a
gastrograffin swallow demonstrated a small leak into the mediastinum.
Mycobacterium were seen on Auramine and Ziehl-Neelsen stains of the
biopsies from the ulcer edge. A mediastinal biopsy grew Mycobacterium
tuberculosis. The patient defervesced rapidly with standard
anti-tuberculosis therapy and the perforation had healed at endoscopic
follow-up one month later.
DE Adult AIDS-Related Opportunistic Infections/*DIAGNOSIS/PATHOLOGY
Biopsy Case Report Esophageal Diseases/*DIAGNOSIS/PATHOLOGY
Esophageal Perforation/*DIAGNOSIS/PATHOLOGY Esophagus/PATHOLOGY Human
Male Mycobacterium tuberculosis/ISOLATION & PURIF Tuberculosis,
Gastrointestinal/*DIAGNOSIS/PATHOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).